Peningkatan Laju Disolusi Dispersi Padat Amorf Genistein dengan PVP K-30
نویسندگان
چکیده
منابع مشابه
افزایش انحلال پذیری کورکومین بااستفاده از پلیمر 30 pvp k-
چکیده برای هزاران سال، کورکومین در شرق به عنوان یک عامل درمانی برای طیف گسترده ای از بیماری های التهابی، نئوپلاستی و دیگر شرایط استفاده شده است. در سال های اخیر، پتانسیل درمانی بزرگی برای این ترکیب در برابر بیماری های مختلف انسان از جمله سرطان، بیماری های قلبی و عروقی، دیابت، ورم مفاصل، بیماری های عصبی و بیماری hivگزارش شده است. این ترکیب اثرات خود را از طریق کاهش بروز فاکتورهای نسخه برداری ا...
Solubilization and Solid-State Characterization of Modafinil Solid Dispersions using PVP K 30
The objective of the present study was to improve the dissolution rate of Modafinil by solid dispersion (SD) systems in PVP-K 30. Drug contents were determined by UV Spectrophotometry at λmax of 259.5 nm. The phase solubility behavior of Modafinil in presence of various concentrations of carriers in distilled water was obtained at 37±2C. The dissolution of Modafinil increased with increasing am...
متن کاملDevelopment of diclofenac sodium-loaded alginate-PVP K 30 microbeads using central composite design
BACKGROUND AND THE PURPOSE OF THE STUDY Diclofenac sodium is a non-steroidal anti-inflammatory agent with a short biological half-life (1-2 hr) and requires multiple dosing. This research was carried out to develop and optimize diclofenac sodium loaded alginate-PVP K 30 microbeads to eliminate the need for multiple dosing and adverse effects. METHODS Diclofenac sodium loaded alginate-PVP K 30...
متن کاملPhysiochemical Characterization and Release Rate Studies of Solid Dispersions of Ketoconazole with Pluronic F127 and PVP K-30
In the present study solid dispersions of the antifungal drug Ketoconazole were prepared with Pluronic F-127 and PVP K-30 with an intention to improve its dissolution properties. Investigations of the properties of the dispersions were performed using release studies, Differential scanning calorimetery (DSC), X-ray powder diffraction (XRD) and Fourier transform infrared (FTIR). The results obta...
متن کاملPhysiochemical Characterization and Release Rate Studies of Solid Dispersions of Ketoconazole with Pluronic F127 and PVP K-30
In the present study solid dispersions of the antifungal drug Ketoconazole were prepared with Pluronic F-127 and PVP K-30 with an intention to improve its dissolution properties. Investigations of the properties of the dispersions were performed using release studies, Differential scanning calorimetery (DSC), X-ray powder diffraction (XRD) and Fourier transform infrared (FTIR). The results obta...
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ژورنال
عنوان ژورنال: Jurnal Sains Farmasi & Klinis
سال: 2017
ISSN: 2442-5435,2407-7062
DOI: 10.29208/jsfk.2017.4.1.197